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Posted By: Cancer Hospital India Although it is over a hundred years since the initial development of laparoscopy, it is only in the past three decades that there has been a revolution in the field with surgeries like laparoscopic cholecystectomy becoming the gold standard worldwide. Advantages of laparoscopic surgery are well known, and include dramatically reduced hospital stay, better patient comfort, rapid return to employment, lesser tissue handling and superior cosmesis compared to open surgery. Further, there is better visualization and magnification especially in areas like the pelvis and the thorax which are often difficult to access in open surgery. Systemic immune competence has also been shown to be better preserved after laparoscopic surgery. The role of laparoscopy for cancer has expanded to include diagnosing, staging, treating, monitoring, and palliating many types of malignancies. Laparoscopic guided biopsy allows the confirmation of malignancy by providing tissue specimens, especially in cases where other means of biopsy are not feasible. Laparoscopic staging can identify unresectable disease, which often dramatically alters therapy. With increased accuracy in staging, many patients can avoid pain and prolonged hospital stay of a nontherapeutic laparotomy For resectable disease, a wide range of curative laparoscopic resections have been described.

Cancer Treatment Hospital Blood And Marrow Transplantation Beyond Barriers Posted By: Cancer Hospital India Introduction Allogeneic Blood and Marrow Transplantation (BMT), which employs the use of hematopoeitic progenitor cells (HPC) from a donor to replace the diseased or defective hematopoeitic as well as the immune system has evolved radically over the last three decades. The indications for Allo-BMT are no longer limited to end-stage leukemias. This is deemed curative and often the only option for many non-malignant conditions as well. These advances have been possible through better understanding and management of post-transplant complications, both infectious and non-infectious. The key to this success is perhaps related to the optimum selection of donors for Allo-BMT. Human Leukocyte Antigen (HLA) system is pivotal to the outcome of Allo-BMT unlike solid organ transplantation. HLA-matched family member was and still is considered the donor of choice for Allo -BMT for all indications; a paradigm which remains unchanged despite tremendous advancements in this field. Based on mendelian laws of inheritance, the chances of siblings being matched to each other at class I and II HLA locus are only 20-30%. Thus 70-80% of patients eligible for an Allo-BMT would be unlikely to find a donor within the family.

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